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Non-human primate regulatory T cells: current biology and implications for transplantation Dons EM; Raimondi G; Cooper DK; Thomson AWTransplantation 2010[Oct]; 90 (8): 811-6Regulatory T cells (Treg) offer potential for improving long-term outcomes in cell and organ transplantation. The non-human primate model is a valuable resource for addressing issues concerning the transfer of Treg therapy to the clinic. Herein, we discuss the properties of non-human primate Treg and prospects for their evaluation in allotransplantation and xenotransplantation.|Adoptive Transfer/methods[MESH]|Animals[MESH]|Antigens, CD/analysis[MESH]|Cell Division[MESH]|Flow Cytometry[MESH]|Humans[MESH]|Immunologic Memory[MESH]|Immunosuppressive Agents/therapeutic use[MESH]|Lymphocyte Activation[MESH]|Lymphocyte Depletion[MESH]|Macaca fascicularis[MESH]|Primates[MESH]|Rodentia[MESH]|T-Lymphocytes, Regulatory/cytology/immunology/*physiology/*transplantation[MESH]|Transplantation, Heterologous/*immunology[MESH] |
