Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Impact of abdominopelvic CT on Ewing sarcoma management Dobbs MD; Lowas SR; Hernanz-Schulman M; Holt GE; Yu C; Kan JHAcad Radiol 2010[Oct]; 17 (10): 1288-91RATIONALE AND OBJECTIVES: Abdominopelvic computed tomography (APCT) is often performed in patients with skeletal Ewing sarcoma family of tumors during initial staging and for subsequent clinical indications, such as metastasis surveillance; however, its clinical impact is unknown. The purpose of this study was to evaluate whether these computed tomographic examinations alter oncologic management and therefore patient outcomes. MATERIALS AND METHODS: One hundred eight consecutive patients with skeletal Ewing sarcoma family of tumors seen from 1985 to 2008 were retrospectively reviewed to identify imaging workup, pathology, primary site, evidence of metastatic disease, and patient outcomes. Data were analyzed using Wilcoxon's rank sum tests. RESULTS: Sixty-five of the 108 patients (60%) underwent 342 abdominopelvic computed tomographic examinations during a mean follow-up period of 8.9 years. During this time period, only one of the 65 patients (1.5%) who underwent APCT was discovered to have abdominal metastatic disease. There was no significant difference in the incidence of metastatic disease to the skeleton or chest between the groups without and with APCT (P = .10). There were 26 pelvic and lumbosacral primaries (24%) and 82 limb primaries (76%). Subgroup analysis performed on the 82 patients with limb primaries without (n = 36) and with (n = 46) APCT showed no significant differences in metastatic incidence to the skeleton or chest (P = .14). CONCLUSIONS: This study indicates that APCT, associated with increased radiation exposure and health expenditure, has a limited role in initial staging and follow-up in patients with skeletal Ewing sarcoma, particularly in patients with limb primaries.|Abdominal Neoplasms/*diagnostic imaging/epidemiology/*secondary[MESH]|Adolescent[MESH]|Adult[MESH]|Bone Neoplasms/*diagnostic imaging/epidemiology[MESH]|Child[MESH]|Child, Preschool[MESH]|Female[MESH]|Humans[MESH]|Incidence[MESH]|Infant[MESH]|Male[MESH]|Middle Aged[MESH]|Pelvic Neoplasms/*diagnostic imaging/epidemiology/*secondary[MESH]|Radiography, Abdominal/statistics & numerical data[MESH]|Radiography, Thoracic/statistics & numerical data[MESH]|Reproducibility of Results[MESH]|Risk Assessment[MESH]|Risk Factors[MESH]|Sarcoma, Ewing/*diagnostic imaging/epidemiology/*secondary[MESH]|Sensitivity and Specificity[MESH]|South Carolina/epidemiology[MESH]|Tomography, X-Ray Computed/*statistics & numerical data[MESH]|Young Adult[MESH] |