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lüll Clinical practice The care of children with Down syndrome Weijerman ME; de Winter JPEur J Pediatr 2010[Dec]; 169 (12): 1445-52Down syndrome (DS) is one of the most common chromosomal abnormalities. Because of medical advances and improvements in overall medical care, the median survival of individuals with DS has increased considerably. This longer life expectancy requires giving the necessary care to the individual with DS over their total longer lifespan. DS medical guidelines are designed for the optimal care of the child in whom a diagnosis of DS has been confirmed. We present an overview of the most important issues related to children with DS based on the most relevant literature currently available.|*Life Expectancy[MESH]|Cardiovascular Diseases/epidemiology/genetics/*therapy[MESH]|Caregivers[MESH]|Child[MESH]|Comorbidity[MESH]|Delivery of Health Care/standards[MESH]|Down Syndrome/complications/diagnosis/epidemiology/*mortality/*therapy[MESH]|Gastrointestinal Diseases/epidemiology/genetics/therapy[MESH]|Humans[MESH]|Otorhinolaryngologic Diseases/epidemiology/genetics/therapy[MESH]|Parents[MESH]|Practice Guidelines as Topic/standards[MESH]|Prevalence[MESH]|Respiratory Tract Diseases/epidemiology/genetics/*therapy[MESH]|Risk Factors[MESH]|Vision Disorders/epidemiology/genetics/*therapy[MESH] |