free     free     free  :  Publisher English Wikipedia <ref>{{Cite pmid|20630771}}</ref> Nephropedia Template TP ( {{tp|p=20630771|t=Molecular and cellular basis of T cell lineage commitment |pdf=|usr=|}} Twit Text Molecular and cellular basis of T cell lineage commitment http://www.kidney.de/pget.php?&tw=1&pmid=20630771 DeepDyve Pubget Overpricing

lüll Molecular and cellular basis of T cell lineage commitment Vicente R; Swainson L; Marty-Gres S; De Barros SC; Kinet S; Zimmermann VS; Taylor N Semin Immunol 2010[Oct]; 22 (5): 270-5 The thymus forms as an alymphoid thymic primordium with T cell differentiation requiring the seeding of this anlage. This review will focus on the characteristics of the hematopoietic progenitors which colonize the thymus and their subsequent commitment/differentiation, both in mice and men. Within the thymus, the interplay between Notch1 and IL-7 signals is crucial for the orchestration of T cell development, but the precise requirements for these factors in murine and human thympoeisis are not synonymous. Recent advances in our understanding of the mechanisms regulating precursor entry and their maintenance in the thymus will also be presented. |*Cell Lineage[MESH] |Animals[MESH] |Cell Differentiation[MESH] |Humans[MESH] |Interleukin-7/immunology/metabolism[MESH] |Receptor, Notch1/immunology/metabolism[MESH] |T-Lymphocytes/*cytology/*immunology[MESH]

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*<b>[http://www.kidney.de/mlpefetch.php?search=20630771 Molecular and cellular basis of T cell lineage commitment ]</b> Semin Immunol 2010; 22(5) ; 270-5 Vicente R; Swainson L; Marty-Gres S; De Barros SC; Kinet S; Zimmermann VS; Taylor N

    *20630771*

Nephropedia PMID record
{{recpmid|pmid=20630771|ti=Molecular and cellular basis of T cell lineage commitment |au=Vicente R; Swainson L; Marty-Gres S; De Barros SC; Kinet S; Zimmermann VS; Taylor N|so=Semin Immunol 2010; 22 (5): 270-5|ab=The thymus forms as an alymphoid thymic primordium with T cell differentiation requiring the seeding of this anlage. This review will focus on the characteristics of the hematopoietic progenitors which colonize the thymus and their subsequent commitment/differentiation, both in mice and men. Within the thymus, the interplay between Notch1 and IL-7 signals is crucial for the orchestration of T cell development, but the precise requirements for these factors in murine and human thympoeisis are not synonymous. Recent advances in our understanding of the mechanisms regulating precursor entry and their maintenance in the thymus will also be presented.}}
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{{BibRecord | Autor = Vicente R; Swainson L; Marty-Gres S; De Barros SC; Kinet S; Zimmermann VS; Taylor N | Titel = Molecular and cellular basis of T cell lineage commitment | Band = 22 | Nummer = 5 | Jahr = 2010 | Monat = Oct | Sprache = eng | DOI = | Seite = 270-5 | PMID = 20630771 | Typ= {{{Typ|}}} | Kommentar = {{{Kommentar|}}} | format = {{{format|}}} | record = {{{record|}}} }}

Semin Immunol