Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
 free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 free
 free
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Unexpected roles for core promoter recognition factors in cell-type-specific transcription and gene regulation Goodrich JA; Tjian RNat Rev Genet 2010[Aug]; 11 (8): 549-58The eukaryotic core promoter recognition complex was generally thought to play an essential but passive role in the regulation of gene expression. However, recent evidence now indicates that core promoter recognition complexes together with 'non-prototypical' subunits may have a vital regulatory function in driving cell-specific programmes of transcription during development. Furthermore, new roles for components of these complexes have been identified beyond development; for example, in mediating interactions with chromatin and in maintaining active gene expression across cell divisions.|*Promoter Regions, Genetic[MESH]|*Transcription, Genetic[MESH]|*Transcriptional Activation[MESH]|Animals[MESH]|Cell Differentiation/genetics[MESH]|DNA/genetics/metabolism[MESH]|Embryonic Development/genetics[MESH]|Female[MESH]|Germ Cells/cytology/metabolism[MESH]|Humans[MESH]|Male[MESH]|RNA Polymerase II/metabolism[MESH]|Transcription Factors/genetics/metabolism[MESH] |
