Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
free free
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Regulation of cellular chromatin state: insights from quiescence and differentiation Srivastava S; Mishra RK; Dhawan JOrganogenesis 2010[Jan]; 6 (1): 37-47The identity and functionality of eukaryotic cells is defined not just by their genomic sequence which remains constant between cell types, but by their gene expression profiles governed by epigenetic mechanisms. Epigenetic controls maintain and change the chromatin state throughout development, as exemplified by the setting up of cellular memory for the regulation and maintenance of homeotic genes in proliferating progenitors during embryonic development. Higher order chromatin structure in reversibly arrested adult stem cells also involves epigenetic regulation and in this review we highlight common trends governing chromatin states, focusing on quiescence and differentiation during myogenesis. Together, these diverse developmental modules reveal the dynamic nature of chromatin regulation providing fresh insights into the role of epigenetic mechanisms in potentiating development and differentiation.|*Gene Expression Regulation, Developmental[MESH]|Adult Stem Cells/physiology[MESH]|Animals[MESH]|Body Patterning[MESH]|Cell Differentiation/genetics/*physiology[MESH]|Cell Growth Processes/physiology[MESH]|Chromatin/genetics/*physiology[MESH]|Epigenesis, Genetic[MESH]|Humans[MESH]|Muscle Development/genetics/physiology[MESH]|Resting Phase, Cell Cycle/genetics/physiology[MESH] |