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  • Modulation of natural killer cell activity by viruses
  • Lisnic VJ; Krmpotic A; Jonjic S
  • Curr Opin Microbiol 2010[Aug]; 13 (4): 530-9
  • Since their discovery, our understanding of NK cells has evolved from branding them marginal innate immunity cells to key players in anti-viral and anti-tumor immunity. Importance of NK cells in control of various viral infections is perhaps best illustrated by the existence of plethora of viral mechanisms aimed to modulate their function. These mechanisms include not only virally encoded immunoevasion proteins but also viral miRNA. Moreover, the evidence has been accumulated supporting the role of viral immunoevasion of NK cells in viral pathogenesis in vivo.
  • |Animals[MESH]
  • |Humans[MESH]
  • |Immune Evasion[MESH]
  • |Killer Cells, Natural/*immunology/virology[MESH]
  • |MicroRNAs/immunology/metabolism[MESH]
  • |Proteins/immunology/metabolism[MESH]
  • |RNA, Viral/immunology/metabolism[MESH]
  • |Receptors, Natural Killer Cell/immunology/metabolism[MESH]
  • |Virus Diseases/immunology/*virology[MESH]
  • |Viruses/*immunology[MESH]

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    *<b>[ Modulation of natural killer cell activity by viruses ]</b> Curr Opin Microbiol 2010; 13(4) ; 530-9 Lisnic VJ; Krmpotic A; Jonjic S


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    Curr Opin Microbiol

    530 4.13 2010