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lüll Bacteriocin as weapons in the marine animal-associated bacteria warfare: inventory and potential applications as an aquaculture probiotic Desriac F; Defer D; Bourgougnon N; Brillet B; Le Chevalier P; Fleury YMar Drugs 2010[Apr]; 8 (4): 1153-77As the association of marine animals with bacteria has become more commonly recognized, researchers have increasingly questioned whether these animals actually produce many of the bioactive compounds originally isolated from them. Bacteriocins, ribosomally synthesized antibiotic peptides, constitute one of the most potent weapons to fight against pathogen infections. Indeed, bacteriocinogenic bacteria may prevent pathogen dissemination by occupying the same ecological niche. Bacteriocinogenic strains associated with marine animals are a relevant source for isolation of probiotics. This review draws up an inventory of the marine bacteriocinogenic strains isolated from animal-associated microbial communities, known to date. Bacteriocin-like inhibitory substances (BLIS) and fully-characterized bacteriocins are described. Finally, their applications as probiotics in aquaculture are discussed.|Animals[MESH]|Anti-Bacterial Agents/pharmacology[MESH]|Aquaculture/methods[MESH]|Bacteria/isolation & purification/metabolism[MESH]|Bacterial Infections/*prevention & control/veterinary[MESH]|Bacteriocins/*pharmacology[MESH]|Humans[MESH]|Probiotics/*pharmacology[MESH] |