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lüll New technology for rapid molecular diagnosis of bloodstream infections Ecker DJ; Sampath R; Li H; Massire C; Matthews HE; Toleno D; Hall TA; Blyn LB; Eshoo MW; Ranken R; Hofstadler SA; Tang YWExpert Rev Mol Diagn 2010[May]; 10 (4): 399-415Technologies for the correct and timely diagnosis of bloodstream infections are urgently needed. Molecular diagnostic methods have yet to have a major impact on the diagnosis of bloodstream infections; however, new methods are being developed that are beginning to address key issues. In this article, we discuss the key needs and objectives of molecular diagnostics for bloodstream infections and review some of the currently available methods and how these techniques meet key needs. We then focus on a new method that combines nucleic acid amplification with mass spectrometry in a novel approach to molecular diagnosis of bloodstream infections.|*Molecular Diagnostic Techniques/instrumentation/methods[MESH]|Aged[MESH]|Bacteremia/*diagnosis[MESH]|Child[MESH]|Child, Preschool[MESH]|DNA, Bacterial/*blood[MESH]|DNA, Fungal/*blood[MESH]|Female[MESH]|Fungemia/*diagnosis[MESH]|Genotype[MESH]|Humans[MESH]|Infant[MESH]|Male[MESH]|Middle Aged[MESH]|Nucleic Acid Amplification Techniques[MESH]|Spectrometry, Mass, Electrospray Ionization/methods[MESH]|Young Adult[MESH] |