Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
 free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 free
 free
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Role of PD-1 in regulating acute infections Brown KE; Freeman GJ; Wherry EJ; Sharpe AHCurr Opin Immunol 2010[Jun]; 22 (3): 397-401While the role of PD-1 in inhibiting immunity during chronic infections is well established, its functions during acute infections are much less clear. The PD-1 pathway can dampen CD8 T cell responses during some acute infections and restrain responses by 'helpless' CD8 memory T cells. An emerging role for PD-1 in innate immunity has been revealed by recent studies showing that PD-1 can limit function of DC and macrophages as well as T cell independent B cell responses. Thus, PD-1 can influence adaptive immune responses during acute infections, though precisely how this regulation occurs is only just beginning to be appreciated.|Acute Disease[MESH]|Animals[MESH]|Antigens, Differentiation/*metabolism[MESH]|Cell Differentiation[MESH]|Gene Expression Regulation/*immunology[MESH]|Humans[MESH]|Immunologic Memory[MESH]|Infections/etiology/*immunology/metabolism[MESH]|Lymphocyte Activation[MESH]|Mice[MESH]|Programmed Cell Death 1 Receptor[MESH]|T-Lymphocytes/cytology/immunology/metabolism[MESH] |
