Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
 free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 free
 free
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Nuclear receptor Rev-erbalpha: a heme receptor that coordinates circadian rhythm and metabolism Yin L; Wu N; Lazar MANucl Recept Signal 2010[Apr]; 8 (ä): e001Nuclear receptor Rev-erbalpha (NR1D1), previously considered to be an orphan nuclear receptor, is a receptor for heme, which promotes transcriptional repression via recruitment of the NCoR-HDAC3 corepressor complex. Rev-erbalpha gene regulation is circadian, and Rev-erbalpha comprises a critical negative limb of the core circadian clock by directly repressing the expression of the positive clock component, Bmal1. Rev-erbalpha also regulates the metabolic gene pathway, thus serving as a heme sensor for coordination of circadian and metabolic pathways.|*Models, Biological[MESH]|Animals[MESH]|Cell Nucleus/*physiology[MESH]|Circadian Rhythm/*physiology[MESH]|Energy Metabolism/*physiology[MESH]|Humans[MESH]|Nuclear Receptor Subfamily 1, Group D, Member 1/*metabolism[MESH]|Signal Transduction/*physiology[MESH] |
