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lüll Definitions and incidence of cardiac syndrome X: review and analysis of clinical data Vermeltfoort IA; Raijmakers PG; Riphagen II; Odekerken DA; Kuijper AF; Zwijnenburg A; Teule GJClin Res Cardiol 2010[Aug]; 99 (8): 475-81There is no consensus regarding the definition of cardiac syndrome X (CSX). We systematically reviewed recent literature using a standardized search strategy. We included 57 articles. A total of 47 studies mentioned a male/female distribution. A meta-analysis yielded a pooled proportion of females of 0.56 (n = 1,934 patients, with 95% confidence interval: 0.54-0.59). As much as 9 inclusion criteria and 43 exclusion criteria were found in the 57 articles. Applying these criteria to a population with normal coronary angiograms and treated in 1 year at a general hospital, the attributable CSX incidence varied between 3 and 11%. The many inclusion and exclusion criteria result in a wide range of definitions of CSX and these have large effects on the incidence. This shows the need for a generally accepted definition of CSX.|*Terminology as Topic[MESH]|Female[MESH]|Humans[MESH]|Incidence[MESH]|Male[MESH]|Microvascular Angina/*classification/*epidemiology[MESH] |