Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
free free
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll RNA traffic control of chromatin complexes Koziol MJ; Rinn JLCurr Opin Genet Dev 2010[Apr]; 20 (2): 142-8It is widely accepted that the genome is regulated by histone modifications that induce epigenetic changes on the genome. However, it is still not understood how ubiquitously expressed chromatin modifying complexes are 'guided' to specific genomic sites to induce intricate patterns of epigenetic modifications. Previously believed to represent 'genome junk', it is now becoming increasingly clear that large non-coding RNAs associate with chromatin modifying complexes. Here we explore an intriguing hypothesis that large non-coding RNA molecules might represent a molecular trafficking system that modulates chromatin modifying complexes to establish specific epigenetic landscapes.|*Models, Genetic[MESH]|Animals[MESH]|Chromatin/*metabolism[MESH]|Epigenesis, Genetic/*genetics[MESH]|Gene Expression Regulation[MESH]|Genomic Imprinting[MESH]|Homeodomain Proteins/genetics[MESH]|Humans[MESH]|RNA, Untranslated/genetics/*metabolism[MESH]|X Chromosome Inactivation[MESH] |