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lüll Genetics of atrial fibrillation Lubitz SA; Yi BA; Ellinor PTHeart Fail Clin 2010[Apr]; 6 (2): 239-47Recent studies of atrial fibrillation (AF) have identified mutations in a series of ion channels; however, these mutations appear to be relatively rare causes of AF. A genome-wide association study has identified novel variants on chromosome 4 associated with AF, although the mechanism of action for these variants remains unknown. Ultimately, a greater understanding of the genetics of AF should yield insights into novel pathways, therapeutic targets, and diagnostic testing for this common arrhythmia.|Arrhythmias, Cardiac/genetics[MESH]|Atrial Fibrillation/epidemiology/*genetics[MESH]|Genome-Wide Association Study[MESH]|Humans[MESH]|Ion Channels/genetics[MESH]|KCNQ1 Potassium Channel/genetics[MESH]|Mutation[MESH]|Potassium Channels, Voltage-Gated/genetics[MESH]|Risk Factors[MESH]|United States/epidemiology[MESH] |