Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
The potential role of muscle in bone repair Liu R; Schindeler A; Little DGJ Musculoskelet Neuronal Interact 2010[Mar]; 10 (1): 71-6Bone repair is a complex phenomenon involving many cell types and signaling factors. Substantial evidence exists to suggest that stem cells originating from local osseous tissues, particularly the periosteum, can contribute to bone repair. However, there are situations where injury or post-surgical management can deplete the amount of, and/or access to these crucial progenitors. The fact that bone repair can still occur in these circumstances implicitly reflects the existence of compensatory secondary systems. One potential alternate source of osteoprogenitors is muscle, which is closely associated with bone and typically suffers trauma during an orthopedic insult. While muscle access is known to be beneficial to bone repair, this is conventionally credited to its high vascularity, and thus its contribution to the local blood supply. However, there is emerging evidence to suggest that progenitors from muscle may directly contribute to bone healing. Defining the role of muscle in bone formation and repair has significant clinical implications, particularly where promoting access to this tissue may enhance the repair outcome.|Animals[MESH]|Bone Regeneration/*physiology[MESH]|Bone and Bones/cytology/*metabolism[MESH]|Fractures, Bone/metabolism/physiopathology[MESH]|Humans[MESH]|Intercellular Signaling Peptides and Proteins/metabolism[MESH]|Muscle Fibers, Skeletal/metabolism[MESH]|Muscle, Skeletal/cytology/*metabolism[MESH]|Osteogenesis/*physiology[MESH]|Periosteum/metabolism[MESH]|Stem Cells/cytology/metabolism[MESH]|Wound Healing/physiology[MESH] |
