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  • An overview of currently available anti-insulin-like growth factor I receptor antibodies
  • Kusada Y; Fujita-Yamaguchi Y
  • Biosci Trends 2007[Dec]; 1 (3): 128-33
  • A number of studies during the last two decades revealed that the insulin-like growth factor I receptor (IGFIR) is an attractive target for cancer molecular therapy. Different molecular strategies have been developed and evaluated in experimental systems, and one such strategy involves anti-IGFIR antibodies, which have been rigorously tested for their therapeutic potential over the last 5-6 years. This mini-review thus introduces currently available IGFIR antibodies with a particular emphasis on epitope mapping and anti-IGFIR antibody-induced cancer growth inhibition.
  • |Animals[MESH]
  • |Antibodies/immunology/*therapeutic use[MESH]
  • |Epitope Mapping/methods[MESH]
  • |Humans[MESH]
  • |Models, Biological[MESH]
  • |Neoplasms/*therapy[MESH]
  • |Receptor, IGF Type 1/*immunology[MESH]





  • *{{pmid20103882}}
    *<b>[http://www.kidney.de/mlpefetch.php?search=20103882 An overview of currently available anti-insulin-like growth factor I receptor antibodies ]</b> Biosci Trends 2007; 1(3) ; 128-33 Kusada Y; Fujita-Yamaguchi Y

        *20103882*

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    Biosci Trends

    128 3.1 2007