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lüll Mediators of ocular angiogenesis Qazi Y; Maddula S; Ambati BKJ Genet 2009[Dec]; 88 (4): 495-515Angiogenesis is the formation of new blood vessels from pre-existing vasculature. Pathologic angiogenesis in the eye can lead to severe visual impairment. In our review, we discuss the roles of both pro-angiogenic and anti-angiogenic molecular players in corneal angiogenesis, proliferative diabetic retinopathy, exudative macular degeneration and retinopathy of prematurity, highlighting novel targets that have emerged over the past decade.|Animals[MESH]|Corneal Neovascularization/*genetics/metabolism[MESH]|Eye/*blood supply[MESH]|Fibroblast Growth Factor 2/genetics/metabolism[MESH]|Humans[MESH]|Matrix Metalloproteinases/genetics/metabolism[MESH]|Polymorphism, Genetic[MESH]|Retinal Neovascularization/*genetics/metabolism[MESH]|Retinal Vessels/growth & development/*metabolism[MESH]|Vascular Endothelial Growth Factor A/genetics/metabolism[MESH] |