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lüll Cell-seeding techniques in vascular tissue engineering Villalona GA; Udelsman B; Duncan DR; McGillicuddy E; Sawh-Martinez RF; Hibino N; Painter C; Mirensky T; Erickson B; Shinoka T; Breuer CKTissue Eng Part B Rev 2010[Jun]; 16 (3): 341-50Previous studies have demonstrated the benefits of cell seeding in the construction of tissue-engineered vascular grafts (TEVG). However, seeding methods are diverse and no method is clearly superior in either promoting seeding efficiency or improving long-term graft function. As we head into an era during which a variety of different TEVG are under investigation in clinical trials around the world, it is important to consider the regulatory issues surrounding the translation of these technologies. In this review, we summarize important advances in the field of vascular tissue engineering, with particular attention on cell-seeding techniques for TEVG development and special emphasis placed on regulatory issues concerning the clinical translation of these various methods.|*Tissue Scaffolds[MESH]|Blood Vessel Prosthesis[MESH]|Blood Vessels/cytology/*physiology[MESH]|Bone Marrow Transplantation/methods[MESH]|Cell Culture Techniques/instrumentation/methods[MESH]|Cell Transplantation/*methods[MESH]|Endothelial Cells/transplantation[MESH]|Guided Tissue Regeneration/instrumentation/methods[MESH]|Humans[MESH]|Models, Biological[MESH]|Myocytes, Smooth Muscle/cytology/transplantation[MESH]|Tissue Engineering/instrumentation/*methods[MESH] |