Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
 free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 free
 free
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Regulation of adaptive immunity by the innate immune system Iwasaki A; Medzhitov RScience 2010[Jan]; 327 (5963): 291-5Twenty years after the proposal that pattern recognition receptors detect invasion by microbial pathogens, the field of immunology has witnessed several discoveries that have elucidated receptors and signaling pathways of microbial recognition systems and how they control the generation of T and B lymphocyte-mediated immune responses. However, there are still many fundamental questions that remain poorly understood, even though sometimes the answers are assumed to be known. Here, we discuss some of these questions, including the mechanisms by which pathogen-specific innate immune recognition activates antigen-specific adaptive immune responses and the roles of different types of innate immune recognition in host defense from infection and injury.|*Adaptive Immunity[MESH]|*Immunity, Innate[MESH]|Animals[MESH]|Antigen-Presenting Cells/immunology[MESH]|Bacterial Infections/*immunology[MESH]|Humans[MESH]|Ligands[MESH]|Receptors, Pattern Recognition/immunology/*metabolism[MESH]|Signal Transduction[MESH]|Toll-Like Receptors/immunology/metabolism[MESH]|Virus Diseases/*immunology[MESH] |
