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lüll Diverse functions of perineuronal nets Karetko M; Skangiel-Kramska JActa Neurobiol Exp (Wars) 2009[]; 69 (4): 564-77Perineuronal nets represent well-organised components of the extracellular matrix, which are surrounding cell bodies, dendrites, and axon segments of a particular class of neurones as well as forming lattice-like structures. The role of perineuronal nets is not fully elucidated yet. Perineuronal nets may play a beneficial role by stabilizing the extracellular milieu assuring the characteristic features of enveloped neurons and protecting them from the influence of harmful agents. On the other hand, perineuronal nets create a barrier which limits neuronal plasticity and counteracts regeneration. This review examines recent evidence concerning the significance of the occurrence of perineuronal nets.|Animals[MESH]|Extracellular Matrix/metabolism/ultrastructure[MESH]|Mice[MESH]|Nerve Net/anatomy & histology/*physiology[MESH]|Nerve Tissue Proteins/metabolism[MESH]|Neurons/cytology/*metabolism[MESH]|Peripheral Nerves/cytology/*physiology[MESH]|Rats[MESH] |