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lüll Clinical experience with high-viscosity cements for percutaneous vertebral body augmentation: occurrence, degree, and location of cement leakage compared with kyphoplasty Georgy BAAJNR Am J Neuroradiol 2010[Mar]; 31 (3): 504-8BACKGROUND AND PURPOSE: Vertebroplasty is known for its high leakage rate compared with kyphoplasty. In recent preclinical studies, high-viscosity cements were shown to significantly enhance the uniformity of cement filling and decrease the incidence of leakage in cancellous bonelike substrates compared with low-viscosity cements. In this study, the incidence and pattern of cement leakage by using a new high-viscosity cement (Confidence spinal cement system) was compared with that of standard kyphoplasty. MATERIALS AND METHODS: Postoperative radiographs of patients treated with either kyphoplasty or Confidence were analyzed for cement leakage by using a stringent and thorough 4-point scale (none, minimal, moderate, or severe). When leakage was observed, the location of the cement leakage was also recorded and described as diskal, venous, paravertebral, or epidural. Sixty-two consecutive patients with 112 treated levels were included in this retrospective review. There were 46 kyphoplasty- versus 66 Confidence-treated levels, which ranged from T3 to L5. RESULTS: The average vertebral collapse reached 27.9 +/- 20.7% in the Confidence group versus 25.0 +/- 19.1% in the kyphoplasty group. There was no or mild leakage in 92% of Confidence and 91% of the kyphoplasty cases (mild, 39% Confidence versus 50% kyphoplasty). Severe leakage was only reported in 1 (2%) Confidence and 1 (2%) kyphoplasty case. In both cases, the severe leakage was found in the disk space. No significant leakage that required any surgical intervention was noticed. CONCLUSIONS: This finding confirms prior observations that highly viscous cements may increase the safety of vertebral augmentation techniques compared with less viscous cements. The high-viscosity Confidence cement results in a leakage rate comparable with that of kyphoplasty.|Aged[MESH]|Aged, 80 and over[MESH]|Bone Cements/*therapeutic use[MESH]|Extravasation of Diagnostic and Therapeutic Materials[MESH]|Female[MESH]|Fractures, Compression/epidemiology/etiology/*therapy[MESH]|Humans[MESH]|Incidence[MESH]|Male[MESH]|Middle Aged[MESH]|Osteoporosis/complications[MESH]|Postoperative Complications/epidemiology/*etiology[MESH]|Retrospective Studies[MESH]|Risk Factors[MESH]|Spinal Fractures/epidemiology/etiology/*therapy[MESH]|Vertebroplasty/*adverse effects/*methods/statistics & numerical data[MESH]|Viscosity[MESH] |