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lüll Human papillomavirus-associated oropharyngeal cancer: a new clinical entity Nguyen NP; Chi A; Nguyen LM; Ly BH; Karlsson U; Vinh-Hung VQJM 2010[Apr]; 103 (4): 229-36The incidence of oropharyngeal cancers is rising worldwide in both nonsmokers and nondrinkers. Epidemiology studies suggest a strong association between human papillomavirus (HPV) 16 infection, changing sexual behavior and cancer development. Despite initial presentation with locally advanced disease and poorly differentiated histology, HPV-associated oropharyngeal carcinoma is associated with a good prognosis because its response to chemotherapy and radiation. Clinicians should be aware of the risk of oropharyngeal cancer in young people to avoid unnecessary delay in diagnosis and treatment. A history of oral sex should be elicited in young patients with enlarged neck nodes and/or tonsillar masses.|*Human papillomavirus 16/genetics[MESH]|Adult[MESH]|DNA, Viral/genetics[MESH]|Female[MESH]|Humans[MESH]|Male[MESH]|Oropharyngeal Neoplasms/epidemiology/therapy/*virology[MESH]|Papillomavirus Infections/epidemiology/therapy/*virology[MESH]|Young Adult[MESH] |