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lüll Near-infrared spectroscopy as an index of brain and tissue oxygenation Murkin JM; Arango MBr J Anaesth 2009[Dec]; 103 Suppl 1 (ä): i3-13Continuous real-time monitoring of the adequacy of cerebral perfusion can provide important therapeutic information in a variety of clinical settings. The current clinical availability of several non-invasive near-infrared spectroscopy (NIRS)-based cerebral oximetry devices represents a potentially important development for the detection of cerebral ischaemia. In addition, a number of preliminary studies have reported on the application of cerebral oximetry sensors to other tissue beds including splanchnic, renal, and spinal cord. This review provides a synopsis of the mode of operation, current limitations and confounders, clinical applications, and potential future uses of such NIRS devices.|Brain Ischemia/*diagnosis[MESH]|Cardiac Surgical Procedures[MESH]|Child[MESH]|Confounding Factors, Epidemiologic[MESH]|Endarterectomy, Carotid[MESH]|Humans[MESH]|Monitoring, Intraoperative/*methods[MESH]|Oximetry/methods[MESH]|Oxygen Consumption/*physiology[MESH]|Spectroscopy, Near-Infrared/*methods[MESH] |