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lüll The treatment of HIV-associated nephropathy Kalayjian RCAdv Chronic Kidney Dis 2010[Jan]; 17 (1): 59-71Antiretroviral therapy (ART) preserves kidney function in patients with human immunodeficiency virus (HIV)-associated nephropathy (HIVAN). Emerging data also document substantial renal benefits of ART in the general HIV-infected population, which is associated in part with suppression of HIV-1 viral replication. The extent to which the response to ART differs in persons with HIVAN compared with those with other HIV-associated kidney disorders is unknown. Beneficial effects of corticosteroids and angiotensin-converting enzyme inhibitors on kidney function also are suggested by retrospective cohort studies and uncontrolled trials of patients with HIVAN. Underexposure to ART or inadequate ART dosing in HIV-infected patients with CKD may curtail the optimal benefits that may be derived from this therapy.|AIDS-Associated Nephropathy/*drug therapy[MESH]|Adrenal Cortex Hormones/*therapeutic use[MESH]|Angiotensin-Converting Enzyme Inhibitors/*therapeutic use[MESH]|Anti-Retroviral Agents/*therapeutic use[MESH]|Humans[MESH]|Kidney/drug effects[MESH] |