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Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8+ T cell immunity Rowe M; Zuo JMicrobes Infect 2010[Mar]; 12 (3): 173-81Persistent viruses have mechanisms for modulating the host immune responses that are essential for achieving a lifelong virus-host balance while minimizing the viral pathogenicity. Here we review some of the immune-modulating mechanisms evolved by the ubiquitous but potentially oncogenic Epstein-Barr virus, with particular emphasis on the molecular mechanisms of genes interfering with HLA class I antigen presentation.|*Host-Pathogen Interactions[MESH]|CD8-Positive T-Lymphocytes/*immunology[MESH]|Herpesvirus 4, Human/*immunology/*pathogenicity[MESH]|Histocompatibility Antigens Class I/*immunology[MESH]|Humans[MESH] |
