Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
free free
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Examining the cardiac NK-2 genes in early heart development Bartlett H; Veenstra GJ; Weeks DLPediatr Cardiol 2010[Apr]; 31 (3): 335-41The cardiac NK-2 transcription factors are the vertebrate relatives of the Drosophila tinman gene. Without the Drosophila tinman gene, fruit flies fail to form their heart ("dorsal vessel"), and mutations or altered expression of cardiac NK-2 genes may lead to abnormal heart formation in vertebrates. Although the cardiac NK-2 gene NKX2-5 is recognized as an important factor in cases of human congenital heart disease and heart development in vertebrates, the roles of the other cardiac NK-2 genes are less clear. This report reviews what is known about the cardiac NK-2 genes in cardiac development, comparing studies in several different model systems.|Animals[MESH]|Drosophila/genetics[MESH]|Genes, Regulator/genetics[MESH]|Heart Defects, Congenital/*genetics[MESH]|Heart/*embryology[MESH]|Homeobox Protein Nkx-2.5[MESH]|Homeodomain Proteins/*genetics[MESH]|Humans[MESH]|Transcription Factors/*genetics[MESH]|Xenopus laevis/genetics[MESH] |