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  lüll Methicillin-resistant Staphylococcus aureus in long-term-care facilities Manzur A; Gudiol FClin Microbiol Infect  2009[Dec]; 15 Suppl 7 (ä): 26-30Owing to a high prevalence of methicillin-resistant Staphylococcus aureus (MRSA)  among residents, long-term-care facilities (LTCFs) have become substantial  reservoirs of this microorganism. Few data on the natural history of MRSA  colonization in this setting are available. The cumulative incidence appears to  be approximately 20% per year, and more than half of carriers have persistent  colonization. Several host-related factors, such as antibiotic use, invasive  devices, and poor infection control practices, increase the risk of colonization.  Clinical experience suggests that subsequent MRSA infections are neither frequent  nor severe while colonized residents are living in an LTCF; however, when  admitted to an acute-care centre, colonized individuals may spread MRSA to other  patients and may develop severe infections. Therefore, the epidemiological impact  of the high prevalence of MRSA in these centres is more relevant than the  clinical impact of this colonization for an individual resident. Standard  precautions should be applied as routine infection control measures for all  residents of LTCFs, whereas barrier precautions, cohorting, decolonization and  other measures should be undertaken only for controlling outbreaks of MRSA  infection.|*Long-Term Care[MESH]|Carrier State/epidemiology/microbiology/prevention & control[MESH]|Cross Infection/*epidemiology/*microbiology/prevention & control[MESH]|Humans[MESH]|Incidence[MESH]|Infection Control/methods[MESH]|Methicillin-Resistant Staphylococcus aureus/*isolation & purification[MESH]|Staphylococcal Infections/*epidemiology/*microbiology/prevention & control[MESH] |