Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
free free
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Monkey B virus (Cercopithecine herpesvirus 1) Elmore D; Eberle RComp Med 2008[Feb]; 58 (1): 11-21Macaques are a particularly valuable nonhuman primate model for a wide variety of biomedical research endeavors. B virus (Cercopithecine herpesvirus 1; BV) is an alpha-herpesvirus that naturally infects conventional populations of macaques. Serious disease due to BV is rare in macaques, but when transmitted to humans, BV has a propensity to invade the central nervous system and has a fatality rate greater than 70% if not treated promptly. The severe consequences of human BV infections led to the inclusion of BV in the original NIH list of target viruses for elimination by development of specific pathogen-free rhesus colonies. In macaques and especially in humans, diagnosis of BV infection is not straightforward. Furthermore, development and maintenance of true BV specific pathogen-free macaque colonies has proven dif cult. In this overview we review the natural history of BV in macaques, summarize what is known about the virus at the molecular level, and relate this information to problems associated with diagnosis of BV infections and development of BV-free macaque colonies.|Acquired Immunodeficiency Syndrome/virology[MESH]|Animals[MESH]|Genome, Viral[MESH]|Herpes Simplex/virology[MESH]|Herpesviridae Infections/transmission/*veterinary[MESH]|Herpesvirus 1, Cercopithecine/classification/genetics/pathogenicity/physiology[MESH]|Humans[MESH]|Macaca/virology[MESH]|Models, Biological[MESH]|Open Reading Frames[MESH]|Simian Acquired Immunodeficiency Syndrome/virology[MESH]|Simplexvirus/genetics/pathogenicity[MESH]|Terminal Repeat Sequences/genetics[MESH] |