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lüll Some currently neglected aspects of cholinergic function Whittaker VPJ Mol Neurosci 2010[Jan]; 40 (1-2): 7-11At the request of the organizers of the XIII International Symposium on Cholinergic Mechanisms, I have selected for review three topics not well represented at the meeting: the synthesis, storage, and release of acetylcholine at cholinergic nerve endings; cholinergic-specific antigens; and neuropeptides as cholinergic co-transmitters. The first topic is illustrated by work with two model systems, the electromotor nerve terminals of the electric ray and the myenteric plexus of the guinea-pig ileum, the second by work with Chol-1, a group of cholinergic-specific gangliosides sialylated on their N-acetylgalactosamine residues, and the third by vasoactive intestinal polypeptide which is a co-transmitter at 70% of cholinergic nerve endings in brain and is also present in both of the model cholinergic systems.|Acetylcholine/*physiology[MESH]|Animals[MESH]|Antigens, Surface/metabolism[MESH]|Electric Organ/physiology[MESH]|Gangliosides/metabolism[MESH]|Humans[MESH]|Models, Animal[MESH]|Myenteric Plexus/physiology[MESH]|Peripheral Nervous System/*physiology[MESH]|Presynaptic Terminals/*physiology[MESH]|Synaptic Transmission/*physiology[MESH]|Vasoactive Intestinal Peptide/metabolism[MESH] |