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lüll Voriconazole-associated zygomycosis: a significant consequence of evolving antifungal prophylaxis and immunosuppression practices?Pongas GN; Lewis RE; Samonis G; Kontoyiannis DPClin Microbiol Infect 2009[Oct]; 15 Suppl 5 (ä): 93-7Mucormycosis (zygomycosis) is an uncommon infection that afflicts severely immunocompromised patients and those with poorly controlled diabetes mellitus. A recent increase in the incidence of mucormycosis at many transplant centres has been linked to the introduction and widespread use of voriconazole prophylaxis in these high-risk populations. However, it is not known if this association reflects a true epidemiological link or represents a marker of changing immunosuppression occurring in parallel with the evolution of transplant practices and immunosuppression strategies.|Antifungal Agents/*adverse effects/therapeutic use[MESH]|Chemoprevention/*methods[MESH]|Drug Resistance, Fungal[MESH]|Humans[MESH]|Immunocompromised Host[MESH]|Mucorales/*drug effects[MESH]|Mucormycosis/*etiology[MESH]|Pyrimidines/*adverse effects/therapeutic use[MESH]|Transplantation[MESH]|Triazoles/*adverse effects/therapeutic use[MESH]|Voriconazole[MESH] |