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lüll Sign language in Landau-Kleffner syndrome Deonna T; Prelaz-Girod AC; Mayor-Dubois C; Roulet-Perez EEpilepsia 2009[Aug]; 50 Suppl 7 (ä): 77-82This article reviews the history of sign language (SL) and the rationale for its use in children with profound auditory agnosia due to Landau-Kleffner syndrome (LKS), illustrated by studies of children and adults followed for many years and rare cases from the literature. The reasons that SL was successful and brought some children out of isolation while it could not be implemented in others are discussed. The nowadays earlier recognition and treatment of LKS and better awareness of the crucial need to maintain communication have certainly improved the outcome of affected children. Alternatives to oral language, even for less severe cases, are increasingly accepted. SL can be learned at different ages with a clear benefit, but the ambivalence of the patients and their families with the world and culture of the deaf may sometimes explain its refusal or limited acceptance. There are no data to support the fear that SL learning may delay or prevent oral language recovery in children with LKS. On the contrary, SL may even facilitate this recovery by stimulating functionally connected core language networks and by helping speech therapy and auditory training.|*Sign Language[MESH]|Adolescent[MESH]|Adult[MESH]|Agnosia/*rehabilitation[MESH]|Child[MESH]|Female[MESH]|Humans[MESH]|Landau-Kleffner Syndrome/*rehabilitation[MESH]|Language Development[MESH]|Male[MESH]|Manual Communication[MESH] |