Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
free free
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll T-bet-/- RAG2-/- ulcerative colitis: the role of T-bet as a peacekeeper of host-commensal relationships Garrett WS; Glimcher LHCytokine 2009[Oct]; 48 (1-2): 144-7Inflammatory bowel disease is a disease that reflects a disequilibrium in host-commensal homeostasis. T-bet-/-xRAG2-/- deficient mice develop a spontaneous juvenile ulcerative colitis resulting from a pro-inflammatory response to the commensal microbiota that is dendritic cell and TNF-alpha driven [schematized in Fig. 1]. The TRUC (T-bet-/- RAG2-/- ulcerative colitis) model is discussed in the broader context of the adaptive and innate immune mechanisms that regulate host-commensal relationships within the intestine.|*DNA-Binding Proteins/genetics/immunology[MESH]|*Inflammatory Bowel Diseases/immunology/microbiology[MESH]|*T-Box Domain Proteins/genetics/immunology[MESH]|Animals[MESH]|Dendritic Cells/immunology[MESH]|Homeostasis/*immunology[MESH]|Humans[MESH]|Immune System Phenomena/immunology[MESH]|Intestinal Mucosa/immunology/microbiology/pathology[MESH]|Mice[MESH]|Mice, Knockout[MESH]|T-Lymphocytes, Regulatory/immunology[MESH] |