Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
free free
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll The mitochondrial brain: From mitochondrial genome to neurodegeneration Turnbull HE; Lax NZ; Diodato D; Ansorge O; Turnbull DMBiochim Biophys Acta 2010[Jan]; 1802 (1): 111-21Mitochondrial DNA mutations are an important cause of neurological disease. The clinical presentation is very varied in terms of age of onset and different neurological signs and symptoms. The clinical course varies considerably but in many patients there is a progressive decline, and in some evidence of marked neurodegeneration. Our understanding of the mechanisms involved is limited due in part to limited availability of animal models of disease. However, studies on human post-mortem brains, combined with clinical and radiological studies, are giving important insights into specific neuronal involvement.|*Genome, Mitochondrial[MESH]|*Mutation[MESH]|Animals[MESH]|Brain/metabolism/*pathology[MESH]|DNA, Mitochondrial/metabolism[MESH]|Humans[MESH]|Mitochondria/*chemistry/metabolism[MESH]|Mitochondrial Diseases/*genetics/*pathology[MESH]|Nerve Degeneration/metabolism/*pathology[MESH] |