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lüll Primary nitinol stenting for femoropopliteal disease Mewissen MWJ Endovasc Ther 2009[Apr]; 16 (2 Suppl 2): II63-81The 1- to 2-year primary patency rates associated with self-expanding nitinol stents for the treatment of symptomatic femoropopliteal disease are superior to those for percutaneous transluminal angioplasty (PTA) and the first-generation stainless steel balloon-expandable stents. The advantages of nitinol stents include improved radial strength and flexibility, the ability to recover from being crushed, reduced foreshortening, and (importantly) deployability without balloon dilation of the stent edge (which may decrease the incidence of the edge stenosis, or "candy-wrap" effect, often observed with balloon-expandable stents). The technical success rate associated with primary deployment of nitinol stents is very high, and acute to 6-month patency results are predictably excellent. Prior to the introduction of nitinol stents, the original guidelines (2000) of the multidisciplinary TransAtlantic Inter-Society Consensus (TASC I) recommended only an adjunctive role for femoropopliteal stents following suboptimal PTA. The abbreviated 2007 TASC II report essentially extended this recommendation to nitinol stents. Here, current trials of nitinol stenting in the femoropopliteal segment are discussed, with emphasis on the advantages of primary (and often direct) deployment in selected circumstances dependent on factors including lesion length, lesion location, indication for treatment (critical limb ischemia or claudication, in-stent restenosis, stent-graft restenosis), and the relative appropriateness of other modalities (e.g., covered stents). Technical considerations in primary nitinol stenting are briefly reviewed. Open questions regarding the factors involved in nitinol stent fracture and the possible association of fracture and restenosis are examined in the context of current clinical trials. A new generation of femoropopliteal nitinol stents combining superior durability and flexibility is expected soon. Development and implementation of uniform reporting and surveillance standards is important for optimizing current and future research.|*Alloys[MESH]|*Femoral Artery/diagnostic imaging/physiopathology[MESH]|*Popliteal Artery/diagnostic imaging/physiopathology[MESH]|*Stents[MESH]|Angioplasty, Balloon/adverse effects/*instrumentation[MESH]|Arterial Occlusive Diseases/diagnostic imaging/physiopathology/*therapy[MESH]|Constriction, Pathologic[MESH]|Humans[MESH]|Practice Guidelines as Topic[MESH]|Prosthesis Design[MESH]|Prosthesis Failure[MESH]|Radiography[MESH]|Recurrence[MESH]|Risk Assessment[MESH]|Time Factors[MESH]|Treatment Outcome[MESH]|Vascular Patency[MESH] |