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lüll Transmissible mink encephalopathy - review of the etiology of a rare prion disease Liberski PP; Sikorska B; Guiroy D; Bessen RAFolia Neuropathol 2009[]; 47 (2): 195-204We review here the history, neuropathology, clinical picture and molecular data on transmissible mink encephalopathy (TME). This obscure disease is of utmost importance as it is plausible that it represents a transmission of hidden bovine spongiform encephalopathy (BSE) to mink in the USA. Of special interest is the similarity of L-type of BSE and TME. Furthermore, experimental molecular studies showed the TME strain-specific in vitro conversion in a cell-free system. In addition, we show here for the first time confocal laser microscopy studies of co-localization of PrPd- amyloid plaques and GFAP-expressing astrocytes.|Animals[MESH]|Cattle[MESH]|Encephalopathy, Bovine Spongiform/genetics/pathology/transmission[MESH]|Microscopy, Confocal[MESH]|Mink[MESH]|Prion Diseases/genetics/*pathology/*transmission[MESH]|Prions/*genetics/metabolism[MESH] |