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lüll Methods to analyze real-world databases and registries Kremers HMBull NYU Hosp Jt Dis 2009[]; 67 (2): 193-7Observational studies, administrative database studies, and registries offer a wealth of real-world information, if designed, maintained, and analyzed according to appropriate observational study methodology. This review summarizes basic observational study methods employed in rheumatology and highlights several notable examples. In response to growing interest in real-world effectiveness and safety data, registries are expected to proliferate in the near future. The availability of detailed clinical information in registries coupled with powerful tools for analysis offers promise for timely and accurate information on the safety and effectiveness of rheumatic treatments.|*Databases as Topic/standards[MESH]|*Evidence-Based Medicine/standards[MESH]|*Registries/standards[MESH]|Guidelines as Topic[MESH]|Humans[MESH]|Observation[MESH]|Reproducibility of Results[MESH]|Research Design[MESH]|Rheumatic Diseases/epidemiology/etiology/*therapy[MESH]|Risk Factors[MESH]|Time Factors[MESH]|Treatment Outcome[MESH] |