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Biocomputers: from test tubes to live cells Benenson YMol Biosyst 2009[Jul]; 5 (7): 675-85Biocomputers are man-made biological networks whose goal is to probe and control biological hosts--cells and organisms--in which they operate. Their key design features, informed by computer science and engineering, are programmability, modularity and versatility. While still a work in progress, biocomputers will eventually enable disease diagnosis and treatment with single-cell precision, lead to "designer" cell functions for biotechnology, and bring about a new generation of biological measurement tools. This review describes the intellectual foundation of the "biocomputer" concept as well as surveys the state of the art in the field.|*Computers, Molecular[MESH]|Biotechnology/*methods[MESH]|Cell Physiological Phenomena[MESH]|Logic[MESH]|Models, Molecular[MESH]|Nucleic Acids/chemistry[MESH]|Proteins/chemistry[MESH] |
