Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
 free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 free
 free
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Follicular helper T cells as cognate regulators of B cell immunity McHeyzer-Williams LJ; Pelletier N; Mark L; Fazilleau N; McHeyzer-Williams MGCurr Opin Immunol 2009[Jun]; 21 (3): 266-73Follicular helper T (T(FH)) cells are a class of helper T cells specialized in the cognate control of antigen-specific B cell immunity. Upon first contact with antigen-primed B cells, pregerminal center effector T(FH) cells promote B cell clonal expansion, antibody isotype switch, plasma cell differentiation, and the induction of germinal centers. By contrast, within germinal centers, T(FH) cells regulate the fate of antigen-specific GC B cells expressing high-affinity variant B cell receptors to promote memory B cell and long-lived plasma cell development. Recent studies unravel multiple signals controlling T(FH) development and functional subtypes of antigen-specific T(FH) cells, including memory T(FH) cells that accelerate memory B cell responses to antigen rechallenge in vivo.|Animals[MESH]|B-Lymphocytes/*immunology[MESH]|Germinal Center/cytology/immunology[MESH]|Humans[MESH]|Immunity, Cellular/*immunology[MESH]|Immunologic Memory/immunology[MESH]|Lymphocyte Activation/immunology[MESH]|Models, Immunological[MESH]|T-Lymphocytes, Helper-Inducer/*immunology[MESH] |
