Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
free free
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Redox signaling and protein phosphorylation in mitochondria: progress and prospects Foster DB; Van Eyk JE; Marban E; O'Rourke BJ Bioenerg Biomembr 2009[Apr]; 41 (2): 159-68As we learn more about the factors that govern cardiac mitochondrial bioenergetics, fission and fusion, as well as the triggers of apoptotic and necrotic cell death, there is growing appreciation that these dynamic processes are finely-tuned by equally dynamic post-translational modification of proteins in and around the mitochondrion. In this minireview, we discuss the evidence that S-nitrosylation, glutathionylation and phosphorylation of mitochondrial proteins have important bioenergetic consequences. A full accounting of these targets, and the functional impact of their modifications, will be necessary to determine the extent to which these processes underlie ischemia/reperfusion injury, cardioprotection by pre/post-conditioning, and the pathogenesis of heart failure.|*Protein Processing, Post-Translational[MESH]|Animals[MESH]|Apoptosis[MESH]|Heart Failure/*metabolism/pathology[MESH]|Humans[MESH]|Ischemic Preconditioning, Myocardial[MESH]|Mitochondria, Heart/*metabolism/pathology[MESH]|Mitochondrial Proteins/*metabolism[MESH]|Myocardial Reperfusion Injury/*metabolism/pathology[MESH]|Necrosis[MESH]|Oxidation-Reduction[MESH]|Phosphorylation[MESH] |