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Cardiac resynchronization therapy in heart failure patients: an update Jeevanantham V; Daubert JP; Zareba WCardiol J 2009[]; 16 (3): 197-209Heart failure continues to be a major public health problem with high morbidity and mortality rates, despite the advances in medical treatment. Advanced heart failure patients have severe persistent symptoms and a poor quality of life. Cardiac resynchronization therapy (CRT), an invasive therapy which involves synchronized pacing of both right and left ventricles, improves ventricular conduction delay and left ventricular performance. Several clinical trials of CRT in medically refractory heart failure patients with wide QRS (> 120 ms), left ventricular ejection fraction |*Cardiac Pacing, Artificial[MESH]|*Pacemaker, Artificial[MESH]|Defibrillators, Implantable[MESH]|Electric Countershock/instrumentation[MESH]|Evidence-Based Medicine[MESH]|Heart Failure/mortality/physiopathology/*therapy[MESH]|Humans[MESH]|Patient Selection[MESH]|Practice Guidelines as Topic[MESH]|Quality of Life[MESH]|Recovery of Function[MESH]|Treatment Outcome[MESH]|Ventricular Function, Left[MESH] |
