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lüll Intraneural ganglia: a clinical problem deserving a mechanistic explanation and model Elangovan S; Odegard GM; Morrow DA; Wang H; Hebert-Blouin MN; Spinner RJNeurosurg Focus 2009[Feb]; 26 (2): E11Intraneural ganglion cysts have been considered a curiosity for 2 centuries. Based on a unifying articular (synovial) theory, recent evidence has provided a logical explanation for their formation and propagation. The fundamental principle is that of a joint origin and a capsular defect through which synovial fluid escapes following the articular branch, typically into the parent nerve. A stereotypical, reproducible appearance has been characterized that suggests a shared pathogenesis. In the present report the authors will provide a mechanistic explanation that can then be mathematically tested using a preliminary model created by finite element analysis.|Computer Simulation[MESH]|Finite Element Analysis[MESH]|Ganglion Cysts/etiology/pathology/*physiopathology[MESH]|Humans[MESH]|Joints/innervation/pathology/*physiopathology[MESH]|Peripheral Nerves/pathology/*physiopathology[MESH]|Peripheral Nervous System Diseases/etiology/pathology/*physiopathology[MESH]|Pressure/adverse effects[MESH]|Synovial Fluid/physiology[MESH]|Synovial Membrane/innervation/pathology/*physiopathology[MESH] |