Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
free free
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Is complement good or bad for cancer patients? A new perspective on an old dilemma Markiewski MM; Lambris JDTrends Immunol 2009[Jun]; 30 (6): 286-92Several studies of human cancers have established that chronic and insidious inflammation promotes the process of carcinogenesis and exacerbates the growth of existing tumors. Conversely, acute inflammation seems to have the opposite effect. Recent discoveries indicate that this dualism in the role of inflammation in cancer is mirrored by the effects of the complement system on this disease process. Previous studies have suggested that complement proteins can contribute to the immune surveillance of malignant tumors. However, a very recent study has indicated that complement proteins can also promote tumor growth. Here, we describe our current understanding of the role of complement in tumor development and progression.|Animals[MESH]|Autoimmune Diseases/immunology/pathology[MESH]|Complement Inactivator Proteins/*immunology/metabolism[MESH]|Complement System Proteins/*immunology/metabolism[MESH]|Disease Progression[MESH]|Humans[MESH]|Immunologic Surveillance[MESH]|Inflammation[MESH]|Neoplasms/*immunology/pathology[MESH]|Oxidative Stress[MESH]|Risk Factors[MESH]|Tumor Escape[MESH] |