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lüll Non-myeloablative allogeneic hematopoietic stem cell transplantation Shelburne N; Bevans MSemin Oncol Nurs 2009[May]; 25 (2): 120-8OBJECTIVE: To review the literature related to nonmyeloablative stem cell transplantation (SCT), and the unique characteristics and patient population to which it applies. DATA SOURCES: Research studies, research and clinical reviews, clinical experience. CONCLUSION: Nonmyeloablative SCT has demonstrated effective and safe application in a heterogeneous population not otherwise eligible for an allogeneic transplantation. Although many principles are based on those of conventional myeloablative transplantation, the engraftment kinetics, patient selection, and regimen-related complications are distinct. IMPLICATIONS FOR NURSING PRACTICE: Nurses must be knowledgeable about nonmyeloablative SCT, including the provision of individualized care for a heterogeneous population. This can include non-traditional transplant indications, elderly cancer patients, and those with comorbidities.|Bone Marrow Purging/adverse effects[MESH]|Graft vs Host Disease/etiology/prevention & control[MESH]|Hematopoietic Stem Cell Transplantation/adverse effects/*methods[MESH]|Humans[MESH]|Oncology Nursing[MESH]|Patient Selection[MESH]|Safety[MESH]|Transplantation Conditioning/adverse effects/*methods[MESH]|Transplantation, Homologous/adverse effects/*methods[MESH]|Treatment Outcome[MESH] |