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Search strategies to identify information on adverse effects: a systematic review Golder S; Loke YJ Med Libr Assoc 2009[Apr]; 97 (2): 84-92OBJECTIVES: The review evaluated studies of electronic database search strategies designed to retrieve adverse effects data for systematic reviews. METHODS: Studies of adverse effects were located in ten databases as well as by checking references, hand-searching, searching citations, and contacting experts. Two reviewers screened the retrieved records for potentially relevant papers. RESULTS: Five thousand three hundred thirteen citations were retrieved, yielding 19 studies designed to develop or evaluate adverse effect filters, of which 3 met the inclusion criteria. All 3 studies identified highly sensitive search strategies capable of retrieving over 95% of relevant records. However, 1 study did not evaluate precision, while the level of precision in the other 2 studies ranged from 0.8% to 2.8%. Methodological issues in these papers included the relatively small number of records, absence of a validation set of records for testing, and limited evaluation of precision. CONCLUSIONS: The results indicate the difficulty of achieving highly sensitive searches for information on adverse effects with a reasonable level of precision. Researchers who intend to locate studies on adverse effects should allow for the amount of resources and time required to conduct a highly sensitive search.|*Databases, Factual/classification[MESH]|*Drug-Related Side Effects and Adverse Reactions[MESH]|*Vocabulary, Controlled[MESH]|Abstracting and Indexing/statistics & numerical data[MESH]|Guidelines as Topic[MESH]|Humans[MESH]|Information Storage and Retrieval/*methods[MESH]|Meta-Analysis as Topic[MESH]|Periodicals as Topic[MESH]|Quality Control[MESH]|Research Design[MESH]|Review Literature as Topic[MESH] |
