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Pediatric liver transplantation Spada M; Riva S; Maggiore G; Cintorino D; Gridelli BWorld J Gastroenterol 2009[Feb]; 15 (6): 648-74In previous decades, pediatric liver transplantation has become a state-of-the-art operation with excellent success and limited mortality. Graft and patient survival have continued to improve as a result of improvements in medical, surgical and anesthetic management, organ availability, immunosuppression, and identification and treatment of postoperative complications. The utilization of split-liver grafts and living-related donors has provided more organs for pediatric patients. Newer immunosuppression regimens, including induction therapy, have had a significant impact on graft and patient survival. Future developments of pediatric liver transplantation will deal with long-term follow-up, with prevention of immunosuppression-related complications and promotion of as normal growth as possible. This review describes the state-of-the-art in pediatric liver transplantation.|Child[MESH]|Family[MESH]|Graft Survival[MESH]|Hepatectomy[MESH]|Humans[MESH]|Liver Diseases/classification/surgery[MESH]|Liver Neoplasms/surgery[MESH]|Liver Transplantation/mortality/standards/*statistics & numerical data[MESH]|Liver/anatomy & histology[MESH]|Living Donors[MESH]|Patient Selection[MESH]|Survival Rate[MESH]|Tissue and Organ Harvesting[MESH] |
