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lüll Centriole evolution Marshall WFCurr Opin Cell Biol 2009[Feb]; 21 (1): 14-9Centrioles are cylindrical structures found at the core of the mitotic spindle pole, which also act as basal bodies to nucleate the formation of cilia. Centrioles have a complex, ninefold symmetric structure, and reproduce by an intriguing duplication process. The complexity and apparent self-reproduction of centrioles raises the question of how such a structure could have evolved, making them a favorite topic for theological speculation by 'intelligent design' creationists. In fact, centrioles are capable of robust self-assembly and can tolerate dramatic perturbations while still maintaining basic functionality. Far from being irreducibly complex, centrioles appear to be based on a rather minimal underlying core structure requiring only a handful of genes to construct.|*Biological Evolution[MESH]|Animals[MESH]|Centrioles/*genetics/physiology[MESH]|Eukaryotic Cells/cytology/physiology[MESH] |