suck pdf from google scholar
unlimited free pdf from europmc19189072    free
PDF from PMC    free
html from PMC    free
PDF vom PMID19189072  :  Publisher
suck pdf from library genesis
English Wikipedia

Nephropedia Template TP (

Twit Text

  • DeepDyve
  • Pubget Overpricing

  • lüll
  • Tumor initiating cells in malignant gliomas: biology and implications for therapy
  • Hadjipanayis CG; Van Meir EG
  • J Mol Med (Berl) 2009[Apr]; 87 (4): 363-74
  • A rare subpopulation of cells within malignant gliomas, which shares canonical properties with neural stem cells (NSCs), may be integral to glial tumor development and perpetuation. These cells, also known as tumor initiating cells (TICs), have the ability to self-renew, develop into any cell in the overall tumor population (multipotency), and proliferate. A defining property of TICs is their ability to initiate new tumors in immunocompromised mice with high efficiency. Mounting evidence suggests that TICs originate from the transformation of NSCs and their progenitors. New findings show that TICs may be more resistant to chemotherapy and radiation than the bulk of tumor cells, thereby permitting recurrent tumor formation and accounting for the failure of conventional therapies. The development of new therapeutic strategies selectively targeting TICs while sparing NSCs may provide for more effective treatment of malignant gliomas.
  • |Animals[MESH]
  • |Brain/pathology[MESH]
  • |Cell Lineage[MESH]
  • |Cell Transformation, Neoplastic[MESH]
  • |Glioma/*pathology/therapy[MESH]
  • |Humans[MESH]
  • |Models, Biological[MESH]
  • |Neoplastic Stem Cells/*pathology[MESH]
  • |Neurons/pathology[MESH]
  • |Stem Cells/pathology[MESH]

  • *{{pmid19189072}}
    *<b>[ Tumor initiating cells in malignant gliomas: biology and implications for therapy ]</b> J Mol Med (Berl) 2009; 87(4) ; 363-74 Hadjipanayis CG; Van Meir EG


    Nephropedia PMID record

    Deutsche Wikipedia - im Artikel

    Hier den unten stehenden Textblock hineinkopieren

    J Mol Med (Berl)

    363 4.87 2009