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The role of tonsillectomy in pediatric IgA nephropathy Mariotti AJ; Agrawal R; Hotaling AJArch Otolaryngol Head Neck Surg 2009[Jan]; 135 (1): 85-7OBJECTIVES: To review pediatric cases of IgA nephropathy (IgAN) in 6 patients who underwent tonsillectomy and had marked improvement of their renal symptoms and to review the appropriate indications for tonsillectomy for this disease. DESIGN: Retrospective case series. SETTING: Academic medical center. PATIENTS: Six children (age range, 8-15 years) with renal biopsy-proved IgAN who were referred by a pediatric nephrologist for recurrent tonsillitis. INTERVENTION: Tonsillectomy. MAIN OUTCOME MEASURES: Resolution of clinical features of IgAN, including proteinuria, gross and microscopic hematuria, and stabilization of renal function. RESULTS: The 6 patients in this series had marked clinical and laboratory improvement of their nephropathy. CONCLUSIONS: In a select group of pediatric cases of IgAN with mild to moderate disease and recurrent tonsillitis, tonsillectomy can be a useful adjuvant treatment to improve urinary symptoms and renal function. IgA nephropathy is a common indication for tonsillectomy in Japan but is seen less often in the United States. Otolaryngologists should be aware of this indication for tonsillectomy.|Adolescent[MESH]|Child[MESH]|Female[MESH]|Glomerulonephritis, IGA/*epidemiology/metabolism/*pathology[MESH]|Humans[MESH]|Immunoglobulin A/metabolism[MESH]|Immunoglobulin G/metabolism[MESH]|Kidney Glomerulus/pathology[MESH]|Male[MESH]|Palatine Tonsil/metabolism[MESH]|Retrospective Studies[MESH]|Tonsillectomy/*methods/*statistics & numerical data[MESH]|Tonsillitis/*epidemiology/*surgery[MESH] |
