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Voriconazole use for endemic fungal infections Freifeld A; Proia L; Andes D; Baddour LM; Blair J; Spellberg B; Arnold S; Lentnek A; Wheat LJAntimicrob Agents Chemother 2009[Apr]; 53 (4): 1648-51In a retrospective review of 24 patients with histoplasmosis, blastomycosis, or coccidioidomycosis treated with voriconazole (most for salvage therapy), the outcome was favorable (improved or stable) for 22 (95.8%) within 2 months of starting voriconazole and for 20 (83.3%) at the last follow-up. Prospective studies are required to determine its role in the treatment of endemic mycoses.|Adolescent[MESH]|Adult[MESH]|Aged[MESH]|Antifungal Agents/*therapeutic use[MESH]|Blastomycosis/*drug therapy[MESH]|Coccidioidomycosis/*drug therapy[MESH]|Female[MESH]|Histoplasmosis/*drug therapy[MESH]|Humans[MESH]|Male[MESH]|Middle Aged[MESH]|Pyrimidines/*therapeutic use[MESH]|Retrospective Studies[MESH]|Triazoles/*therapeutic use[MESH]|Voriconazole[MESH] |
