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lüll Drug-drug interactions with newer antiretroviral agents Aberg JATop HIV Med 2008[Dec]; 16 (5): 146-50Knowledge of drug interactions among antiretroviral agents and other drugs used by HIV-infected patients is essential to maintaining safety and efficacy of drug treatment. Often, the clinical impact of drug-drug interactions cannot be predicted on the basis of pharmacokinetic interactions alone, highlighting the need for studies and analyses that provide exposure-response data. Drug interactions in HIV-infected patients can be complex and sometimes counterintuitive, and practitioners must increasingly rely on a concerted approach to gathering information on drug interactions that goes beyond studies showing exposure changes for coadministered drugs.|*Drug Interactions[MESH]|Adult[MESH]|Anti-Retroviral Agents/pharmacokinetics/*pharmacology[MESH]|Female[MESH]|Humans[MESH]|Male[MESH]|Middle Aged[MESH] |